![]() Meth or methamphetamine is similar to cocaine. In 2019, more than 16,000 people died of a cocaine overdose. The elimination half-life refers to the amount of time it would take the body to eliminate half of any drug dose administered.Īdditionally, if you use crack or cocaine chronically, the half-life of the drug may increase.Īccording to the Centers for Disease Control and Prevention, overdose deaths from cocaine use are increasing. This fact is important because cocaine metabolites have longer elimination half-lives than cocaine. However, most of the substance will metabolize to different cocaine metabolites (end products of metabolism). Regarding drug metabolism, some cocaine is excreted unchanged in the urine. Therefore, it is not like amphetamines or meth, which can produce long-lasting effects in the body. This observation is different from intranasal cocaine use, i.e., snorting, where peak concentrations don’t occur until 60 minutes have passed.Ĭrack cocaine, although a stimulant, is short-acting. Peak concentrations of crack cocaine will take place within 5-10 minutes of smoking the substance.
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